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| Corporate Governance - Insider Transactions |  |
| Transaction Date | Filer | Filing | Transaction Type | Shares Traded | | 11/11/09 | Dunn Jeff Director Trans History: 2 | Form 4 | Acquisition of Derivative Securities from Company | 2,085 | | 11/09/09 | Chapman Brett General Counsel Trans History: 106 | Form 4 | Sale of Securities | 20,000 | | 10/29/09 | Dunn Jeff Director Trans History: 2 | Form 3 | Statement of Beneficial Ownership | N/A | | 10/20/09 | Henig Yair Steve Chief Scientific Officer Trans History: 29 | Form 4 | Sale of Securities | 5,000 | | 10/20/09 | Henig Yair Steve Chief Scientific Officer Trans History: 29 | Form 4 | Acquisition of Securities through Exercise or Conversion of Derivative Security | 5,000 | | 10/20/09 | Henig Yair Steve Chief Scientific Officer Trans History: 29 | Form 4 | Disposition of Derivative Securities by Exercise or Conversion | 5,000 | | 10/19/09 | Henig Yair Steve Chief Scientific Officer Trans History: 29 | Form 4 | Sale of Securities | 10,000 | | 10/19/09 | Henig Yair Steve Chief Scientific Officer Trans History: 29 | Form 4 | Acquisition of Securities through Exercise or Conversion of Derivative Security | 10,000 | | 10/19/09 | Henig Yair Steve Chief Scientific Officer Trans History: 29 | Form 4 | Disposition of Derivative Securities by Exercise or Conversion | 10,000 | | 10/09/09 | Henig Yair Steve Chief Scientific Officer Trans History: 29 | Form 4 | Sale of Securities | 9,300 |
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| * Represents the number of non-derivative securities directly held | | (I) Indicates that some (or all) of these shares are held indirectly |
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